• Use Schuka, Duke of Amnesia with Eldritch Poison. Once the creature is in the battle zone, destroy it using Eldritch Poison so Schuka's effect will trigger. After discarding your hand the remainder of Eldritch Poison's effect will occur and you'll return a creature from your mana zone to your hand. This combination will allow you to discard all cards from your opponents hand, you won't be in that disadvantage because you will pick up a creature back from your mana zone.

Schuka, Duke of Amnesia
Community content is available under CC-BY-SA unless otherwise noted.