The Loop (Games)
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- Lost Soul can be used well against any form of deck that draws extra cards (such as a deck with cards like Aqua Hulcus or Brain Serum in a control deck, or also alongside them to gain more advantage over your opponent.
- Lost Soul can also be combined with cards such as Spiral Gate or Aqua Surfer to return your opponent's creatures to their hand, where you can then discard them with Lost Soul. Although this can be used against creatures that cannot be attacked in order to discard rather than destroy them (you cannot use this on cards that cannot be targeted such as Petrova, Channeler of Suns).
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